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Anadrol, sold under the brand names Oxymetholone and Anapolon among others, is an androgen and anabolic steroid (AAS) medication which is used primarily in the treatment of anemia. It is also used to treat osteoporosis, HIV/AIDS wasting syndrome, and to promote weight gain and muscle growth in certain situations. It is taken by mouth.

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ANADROL® (oxymetholone) Tablets for oral administration each contain 50 mg of the
6 steroid oxymetholone, a potent anabolic and androgenic drug.
7 The chemical name for oxymetholone is 17β-hydroxy-2-(hydroxymethylene)-17-
8 methyl-5α-androstan-3-one. The structural formula is:

Side effects of Anadrol include increased sexual desire as well as symptoms of masculinization like acne, increased hair growth, and voice changes. It can also cause liver damage. The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). It has strong anabolic effects and weak androgenic effects.

Anadrol was first prescribed in 1959 and was introduced for medical use but was discontinued in 1961 due its high lipid toxicity. It is used mostly in the United States. In addition to its medical use, Anadrole is used to improve physique and performance. The drug is a controlled substance in many countries and so non-medical use is generally illicit.

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Anadrol Medical uses

The primary clinical applications of Anadrol include treatment of anemia and osteoporosis, as well as stimulating muscle growth in malnourished or underdeveloped patients. However, in the United States, the only remaining FDATooltip Food and Drug Administration-approved indication is the treatment of anemia.

Following the introduction of oxymetholone, nonsteroidal drugs such as epoetin alfa were developed and shown to be more effective as a treatment for anemia and osteoporosis without the side effects of Anadrol. The drug remained available despite this and eventually found a new use in treating HIV/AIDS wasting syndrome.

Presented most commonly as a 50 mg tablet, Anadrol has been said to be one of the “strongest” and “most powerful” AAS available for medical use. Similarly, there is a risk of side effects. Anadrol is highly effective in promoting extensive gains in body mass, mostly by greatly improving protein synthesis. For this reason, it is often used by bodybuilders and athletes.

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Bodybuilding / Performance Use (non-medical)

• Anadrol is known as one of the most powerful bulking steroids, often used for rapid gains in size and strength.

• Typical cycle doses (by athletes) range from 25–100 mg/day, though higher doses increase risks.

• It is usually taken for short cycles (4–6 weeks) due to liver toxicity.